Blood Centre at UCT Private Academic Hospital
Welcome to the UCT Private Academic Blood Centre web page. Our Haematology specialists provide expert primary and consultative care for patients with a diverse spectrum of benign and malignant blood-related disorders. Clinical disorders of particular interest include: bone marrow failure disorders (aplastic anaemia, paroxysmal nocturnal hemoglobinuria, myelodysplastic syndromes, pure red cell aplasia, etc.), myeloproliferative disorders (polycythaemia vera, essential thrombocytosis, myelofibrosis), chronic myeloid leukemia, acute leukaemia, coagulation disorders, sickle cell anaemia, and a variety of other benign and malignant diseases.
At the Blood Centre, we provide the most comprehensive and advanced diagnostic and therapeutic services for blood cancers in the region. Based on best available medical evidence treatment plans are individualised for patients to offer optimal clinical management. Our specialists are able to offer focused treatment for all phases and stages of lymphoma, leukemia, and myeloma – including in refractory disease. Treatment approaches for blood cancers may include chemotherapy, radiation oncology, stem cell or marrow transplantation, or immunotherapy. We are associated with an expert haematopathology diagnostic team capable of pathologic review of lymph nodes and bone marrow with in-depth cytogenetic and molecular analysis.
The Blood Centre at UCTPAH plays a unique role as a regional referral resource for difficult and challenging cases, from other colleagues throughout the Western Cape, nationally and from beyond our borders. Our consultants work closely with the staff in the Bone Marrow Transplant service, to provide rapid referral of those patients who are candidates for stem cell transplant.
Anaemia -- The service aids in the diagnosis and management of anaemia, offering consultation on the management of patients with congenital anaemias, such as sickle cell disease.
Neutropenia -- Evaluation and assistance in the management of congenital and acquired causes of neutropenia, including benign neutropenia of childhood, congenital agranulocytosis, and drug-induced neutropenia.
Thrombocytopenia -- Evaluation and management of patients with immune thrombocytopenic purpura (ITP) and other causes of thrombocytopenia.
Coagulation -- Diagnosis and aid in the care of patients with bleeding disorders, such as haemophilia and von Willebrandt's disease. We offer specialized evaluations of individuals with genetic thrombotic conditions.
Leukemia and lymphoma – We provide a comprehensive diagnostic and management service for patients with acute and chronic leukemia, Hodgkin's disease, and non-Hodgkin's lymphomas.
Multiple myeloma – Multiple myeloma remains a common blood disorder, which with appropriate management can be converted into a chronic disease. Suitable patients may be considered for dose intense conditioning and autologous stem cell transplantation.
The Stem cell transplantation program
Stem cell transplants can benefit people with a variety of both cancerous (malignant) and noncancerous diseases. Allogeneic and autologous bone marrow and blood stem cell transplants have been performed at UCT PAH Blood Centre since 2005. Currently the bone marrow and stem cell transplant program offered by the Blood Centre and the University of Cape Town are one of the largest in the continent, and we regularly perform unrelated donor and placental cord blood transplants since 2004.
Our physicians use the latest clinical techniques and resources to harvest stem cells. By manipulating stem cell grafts, they also modify immunity. Dedicated facilities include a 6-bed unit for patients undergoing transplant, which offers ICU beds and special HEPA filtration systems to reduce the risk of infection.
UCT Private Academic Hospital
Tel: +27 (0) 21 442 1856
Fax: +27 (0) 21 448 8607
Other resources about potential donors and transplant centers?
The National Marrow Donor Program® (NMDP), a federally funded non-profit organization, was created to improve the effectiveness of the search for donors. The NMDP and other registries (SABMR) maintain international registries of volunteers willing to be donors of blood stem cells used in transplantation: Bone marrow, peripheral blood, and umbilical cord blood. The NMDP Eurocord and SABMR Web site contains a list of participating transplant centers at http://www.marrow.org/PATIENT/Plan_for_Tx/Choosing_a_TC/ US_NMDP_Transplant_Centers/tc_list_by_state.pl on the Internet. The list includes descriptions of the centers, research interests, pretransplant costs, and contact information.
South African Bone Marrow Registry
PO Box 13353, Mowbray, 7705
Cape Town, South Africa
Tel: +27 (0) 21 404 6445
Fax: +27 (0) 21 404 6395